Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp134 | Female Reproduction | ECE2017

Relugolix, an oral gonadotropin-releasing hormone (GnRH) receptor antagonist, in women with endometriosis (EM)-associated pain: Phase 2 safety and efficacy 24-week results

Osuga Yutaka , Seki Yoshifumi , Tanimoto Masataka , Kusumoto Takeru , Kudou Kentarou , Terakawa Naoki

Objective: The objective of this Phase 2 study was to evaluate the safety of relugolix when administered for 24 weeks in women with EM-associated pain. Efficacy was exploratory assessed using leuprorelin as a reference.Design: This was an open-label extension study evaluating safety of 3 doses (10 mg, 20 mg, and 40 mg) of relugolix administered orally once daily for a total of 24 weeks in women with EM-associated pain, who had participated in a preceding...